Three research projects involving Polish researchers have been awarded funding from the National Science Centre (NCN) in a call launched by the JPND network (EU Joint Programme – Neurodegenerative Disease Research).
The EU Joint Programme – Neurodegenerative Disease Research (JPND) has announced the results of its call for international research projects focused on understanding the mechanisms underlying neurodegenerative diseases and enhancing the ability to measure parameters related to disease progression in its early and pre-symptomatic stages. Among the selected projects are three significant initiatives involving Polish researchers, each offering promising insights into neurodegenerative conditions and potential therapies.
1. IGNITEMIND – IgLON5 Project
The IGNITEMIND project aims to explore immune system irregularities that contribute to the development of a rare autoimmune disorder known as IgLON5 disease. This condition is characterized by the immune system mistakenly targeting the brain, leading to cognitive and physical decline. Polish researchers will conduct comprehensive analyses of immune system involvement throughout various disease stages. This research could pave the way for innovative therapeutic approaches to combat autoimmune dementias and related conditions.
2. Expand-RED Project
The Expand-RED project seeks to advance methods for measuring disease progression in neurodegenerative conditions like Huntington’s disease and spinocerebellar ataxia. Focusing on speech changes in patients at pre-symptomatic, early symptomatic, and symptomatic stages, researchers will apply sophisticated speech assessment tools and biomarker analysis. This project also explores the correlation between speech impairments and motor symptoms, aiming to enhance early detection and intervention for these debilitating diseases.
3. SPARC-AD Project
The SPARC-AD project focuses on the structural characteristics of amyloids, the abnormal protein formations commonly associated with neurodegenerative diseases such as Alzheimer’s. Leveraging advanced imaging techniques paired with artificial intelligence, researchers aim to identify various amyloid types and structural changes. The outcomes of this project are expected to improve diagnostic accuracy for Alzheimer’s disease, leading to earlier and more precise detection.
Source:
Nauka w Polsce
